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Phosphoglycerate dehydrogenase (PHGDH), as a key enzyme in the first step of serine synthesis, is overexpressed in both TNBC and BLBC, in part, because of copy number amplification 50,51

After washes, cells were incubated with AlexaFluor-labeled secondary antibodies and Alexa488- or Alexa647-labeled phalloidin (Invitrogen, diluted at 1:500) diluted in 0.1% (wt/vol) BSA-containing TBS for 1 h at room temperature

Immunosenescence induced by plasma from individuals with obesity caused cell signaling dysfunction and inflammation

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[54] Arsenic trioxide inhibits glutathione peroxidase, thereby decreasing its concentration in the cell, which leads to an increase in the levels of reactive oxygen species